Shares of oncology biotech company Tyra Biosciences

jumped more than 60% on their first day of trading Wednesday. Tyra raised $173 million by offering 10.8 million shares at $16, at the high end of expectations between $14 and $16 and an upsized deal. Tyra is one of several newly minted companies trading on Wednesday above their IPO range and a busy week for initial public offerings, with 2021 shaping up the biggest year ever for IPO proceeds.

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