Gainers

Axcella Health Inc. AXLA shares rose 54.1% to $0.9290 in pre-market trading after the company announced FDA clearance of its IND application to initiate a phase 2b/3 trial in the U.S. for AXA1125.
Boxed, Inc. BOXD rose 37.6% to $0.6089 in pre-market trading after dropping around 8% on Wednesday.
Community Health Systems, Inc. CYH shares rose 21.5% to $6.17 in pre-market trading after the company reported better-than-expected Q4 earnings.
Greenidge Generation Holdings Inc. GREE rose 17.7% to $0.7698 in pre-market trading after gaining 9% on Wednesday.
Emergent BioSolutions Inc. EBS shares rose 14.6% to $17.12 in pre-market trading after the company reported FDA Advisory Committees’ unanimous vote in favor of NARCAN nasal spray, a nonprescription opioid overdose reversal agent for over-the-counter use.
Twilio Inc. TWLO rose 14.3% to $75.59 in pre-market trading after the company reported better-than-expected Q4 sales and announced a $1 billion buyback program.
AIM ImmunoTech Inc. AIM rose 13.8% to $0.5580 in pre-market trading. AIM ImmunoTech recently entered into a sponsored collaborative clinical research agreement with Erasmus MC and AstraZeneca.
AERWINS Technologies Inc. AWIN rose 10.1% to $2.07 in pre-market trading.
Cipher Mining Inc. CIFR rose 8.7% to $1.99 in pre-market trading after jumping over 20% on Wednesday.
Roku, Inc. ROKU rose 9.9% to $69.79 in pre-market trading after the company reported better-than-expected Q4 results. The company added 4.6 million net new native accounts in the quarter.

Losers

Atlis Motor Vehicles, Inc. AMV shares fell 19.4% to $1.37 in pre-market trading after gaining around 10% on Wednesday.
Mercurity Fintech Holding Inc. MFH shares dropped 16.7% to $0.70 in pre-market trading.
Ur-Energy Inc. URG fell 13.6% to $1.13 in pre-market trading after the company reported a proposed public offering of common shares and warrants.
QuantumScape Corporation QS fell 13% to $10.30 in pre-market after the company reported worse-than-expected Q4 EPS.
Iris Energy Limited IREN fell 13% to $3.72 in pre-market trading after the company reported worse-than-expected Q2 results.
Grove Collaborative Holdings, Inc. GROV fell 10.5% to $0.39 in pre-market trading after gaining 7% on Wednesday.
Shopify Inc. SHOP shares fell 10.3% to $47.91 in pre-market trading despite better-than-expected Q4 results. The company also guided revenue growth in the high-teen percentages for Q1.
RingCentral, Inc. RNG fell 9.6% to $43.70 in pre-market trading after the company reported worse-than-expected Q4 revenues and issued weak revenue guidance for Q1
Sera Prognostics, Inc. SERA fell 9.3% to $2.06 in pre-market trading. Sera Prognostics shares jumped 75% on Wednesday after the company announced top-line data from the AVERT PRETERM TRIAL.
ZyVersa Therapeutics, Inc. ZVSA fell 8.1% to $2.28 in pre-market trading after adding 9% on Wednesday.

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